Just a word of warning, most 4x114.3 wheels have low offsets or staggered fitments (most 4x114.3 are RWD). Adding adapters to already low offset would push the wheel out too far. What specs are the wheels that you're thinking of putting on?
Edit: I've used 5x114.3 adapters to use on 5x100 and they're fine. Torque everything down to spec and you shouldn't have any worries, but as I wrote above, make sure the offset you're dealing with is high enough to accommodate adapters and still sit alright under the guards.
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